Services
* Drug discovery - for researchers developing new chemical tools and therapeutic agents, the Core can collaborate on the design and synthesis of small molecules, and the optimization of promising hit and lead compounds. We work with both academic groups and industry, and can manage synthetic chemistry and other activities conducted at external CRO partners.
* Medicinal chemistry consulting - the Core can provide input for grant applications, analyze screening data to prioritize chemical series for further evaluation, search the chemistry and patent literature to assess the IP landscape, and assist with the generation of selectivity, pharmacokinetic and safety data.
* Provision of tool compounds - the Core can source chemical probes for in vitro testing and animal studies. If a compound is not commercially available, the Core can arrange for its custom synthesis.
* Medicinal chemistry consulting - the Core can provide input for grant applications, analyze screening data to prioritize chemical series for further evaluation, search the chemistry and patent literature to assess the IP landscape, and assist with the generation of selectivity, pharmacokinetic and safety data.
* Provision of tool compounds - the Core can source chemical probes for in vitro testing and animal studies. If a compound is not commercially available, the Core can arrange for its custom synthesis.